Lymphocytes shrink to stay fit

Lymphocytes shrink to stay fit

In response to an infection, proinfl ammatory cytokines stimulate lymphocytes to take up nutrients so that they can proliferate and mount an immune response. Once the infection is cleared, however, cytokine levels decline and the lymphocytes’ nutrient supply is abruptly cut off. Most of the cells quickly die by apoptosis, but a small fraction survive and differentiate into longlived memory cell...

How chromosomes shrink to fit

Cells in an early embryo need to downsize their DNA. Ladouceur et al. show that a cell’s size and the size of its nucleus determine how small its chromosomes become (1). Like someone who’s moved from a house to an apartment, cells in an early embryo run into space limitations. The embryo remains the same size for its fi rst few divisions, so the cells have to become much smaller, shrinking by a...

Stay Professionally Fit, Always

Monolithic model of induction shrink fit for high-speed tools

Axisymmetric induction clamping of high-speed machine tools is proposed and modeled. The model consists of three nonlinear partial differential equations (PDEs) describing the distribution of magnetic field, temperature field and field of thermoelastic displacements in the domain. The system is solved numerically in the monolithic formulation using own code Agros2D based on a fully adaptive hig...

Optimization of rotor shaft shrink fit method for motor using “Robust design”

This research is collaborative investigation with the general-purpose motor manufacturer. To review construction method in production process, we applied the parameter design method of quality engineering and tried to approach the optimization of construction method. Conventionally, press-fitting method has been adopted in process of fitting rotor core and shaft which is main component of motor...